Function and Biology

Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC069)

Source organism: Trypanosoma cruzi
Biochemical function: NAD binding
Biological process: malate metabolic process
Cellular component: mitochondrion

Sequence families

Pfam Protein families (Pfam)
PF03949
Domain description: Malic enzyme, NAD binding domain
Occurring in:
  1. Malic enzyme
The deposited structure of PDB entry 6w57 contains 1 copy of Pfam domain PF03949 (Malic enzyme, NAD binding domain) in Malic enzyme. Showing 1 copy in chain A.

PF00390
Domain description: Malic enzyme, N-terminal domain
Occurring in:
  1. Malic enzyme
The deposited structure of PDB entry 6w57 contains 1 copy of Pfam domain PF00390 (Malic enzyme, N-terminal domain) in Malic enzyme. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001891
Domain description: Malic oxidoreductase
Occurring in:
  1. Malic enzyme
IPR012302
Domain description: Malic enzyme, NAD-binding
Occurring in:
  1. Malic enzyme
IPR012301
Domain description: Malic enzyme, N-terminal domain
Occurring in:
  1. Malic enzyme
IPR036291
Domain description: NAD(P)-binding domain superfamily
Occurring in:
  1. Malic enzyme
IPR015884
Domain description: Malic enzyme, conserved site
Occurring in:
  1. Malic enzyme
IPR046346
Domain description: Aminoacid dehydrogenase-like, N-terminal domain superfamily
Occurring in:
  1. Malic enzyme
IPR037062
Domain description: Malic enzyme, N-terminal domain superfamily
Occurring in:
  1. Malic enzyme