› 6wby

Electron Microscopy
3.4Å resolution

Single-Particle Cryo-EM Structure of Arabinofuranosyltransferase AftD from Mycobacteria, Mutant R1389S Class 2

Released:
DOI: 10.2210/pdb6wby/pdb
PDB entry 6wby coloured by chain, front view.
PDB entry 6wby coloured by chain, side view.
PDB entry 6wby coloured by chain, top view.
Source organism: Mycobacteroides abscessus
Primary publication:
Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria.
Tan YZ, Zhang L, Rodrigues J, Zheng RB, Giacometti SI, Rosário AL, Kloss B, Dandey VP, Wei H, Brunton R, Raczkowski AM, Athayde D, Catalão MJ, Pimentel M, Clarke OB, Lowary TL, Archer M, Niederweis M, Potter CS, Carragher B, Mancia F
Mol Cell 78 683-699.e11 (2020)
PMID: 32386575
Related structures: EMD-21601

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105024 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
F5/8 type C domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 1438 amino acids
Theoretical weight: 152.82 KDa
Source organism: Mycobacteroides abscessus
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A418KZ72 (Residues: 1-1410; Coverage: 100%)
Gene name: D2E76_26050
Sequence domains: Alpha-(1->3)-arabinofuranosyltransferase

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-21601
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Better, Faster, Cheaper: Recent Advances in Cryo-Electron Microscopy.
Chua et al. (2022)
6 more

2 mentions without citation

Recent Insights into the Structure and Function of Mycobacterial Membrane Proteins Facilitated by Cryo-EM.
Bendre et al. (2021)
1 more