Function and Biology Details
Reactions catalysed:
Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides
A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Somatomedin B domain
- Somatomedin B domain, chordata
- DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain
- Alkaline-phosphatase-like, core domain superfamily
- Somatomedin B-like domain superfamily
- ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain
- His-Me finger superfamily
- DNA/RNA non-specific endonuclease superfamily
1 more domain
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149626 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (5 distinct):
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Molecule details ›
P22413Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup:
P212121
Expression system: Homo sapiens
