Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- DNA polymerase family X
- DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu
- Nucleotidyltransferase superfamily
- DNA-directed DNA polymerase X
- DNA polymerase lambda lyase domain superfamily
- DNA polymerase beta, thumb domain
- DNA polymerase, thumb domain superfamily
- DNA polymerase family X, binding site
4 more domains
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
DNA-directed DNA/RNA polymerase mu and DNA (preferred)
PDBe Complex ID:
PDB-CPX-120841 (preferred)
Entry contents:
1 distinct polypeptide molecule
4 distinct DNA molecules
4 distinct DNA molecules
Macromolecules (5 distinct):
DNA-directed DNA/RNA polymerase mu
Molecule details ›
Chain: A
Length: 356 amino acids
Theoretical weight: 40.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 356 amino acids
Theoretical weight: 40.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9NP87 (Residues: 132-397, 411-494; Coverage: 71%)
Sequence domains:
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 22-ID
Spacegroup:
P212121
Expression system: Escherichia coli BL21(DE3)
