› 6wis

X-ray diffraction
2Å resolution

Copper resistance protein copG- Form 1

Released:
DOI: 10.2210/pdb6wis/pdb
PDB entry 6wis coloured by chain, front view.
PDB entry 6wis coloured by chain, side view.
PDB entry 6wis coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
The bacterial copper resistance protein CopG contains a cysteine-bridged tetranuclear copper cluster.
Hausrath AC, Ramirez NA, Ly AT, McEvoy MM
J Biol Chem 295 11364-11376 (2020)
PMID: 32571874

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-574766 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DUF411 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 126 amino acids
Theoretical weight: 13.64 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HV84 (Residues: 24-149; Coverage: 99%)
Gene name: PA4714
Sequence domains: Protein of unknown function, DUF

Ligands and Environments

4 bound ligands:
Ligand CU 8 x CU
Ligand GOL 4 x GOL
Ligand ACT 2 x ACT
Ligand ZN 15 x ZN
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P61
Unit cell:
a: 86.13Å b: 86.13Å c: 58.56Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.172 0.22
Expression system: Escherichia coli

Quick links

Citations

1 review citation

From Copper Tolerance to Resistance in Pseudomonas aeruginosa towards Patho-Adaptation and Hospital Success.
Virieux-Petit et al. (2022)
5 other articles

4 mentions without citation

Cu Homeostasis in Bacteria: The Ins and Outs.
Andrei et al. (2020)
3 more