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Structure of human TRPA1 in complex with inhibitor GDC-0334

Source organism: Homo sapiens
Biochemical function: monoatomic ion channel activity
Biological process: transmembrane transport
Cellular component: membrane

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00023
Domain description: Ankyrin repeat
Occurring in:
  1. Transient receptor potential cation channel subfamily A member 1
The deposited structure of PDB entry 6wj5 contains 12 copies of Pfam domain PF00023 (Ankyrin repeat) in Transient receptor potential cation channel subfamily A member 1. Showing 3 copies in chain A.

PF00520
Domain description: Ion transport protein
Occurring in:
  1. Transient receptor potential cation channel subfamily A member 1
The deposited structure of PDB entry 6wj5 contains 4 copies of Pfam domain PF00520 (Ion transport protein) in Transient receptor potential cation channel subfamily A member 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002110
Domain description: Ankyrin repeat
Occurring in:
  1. Transient receptor potential cation channel subfamily A member 1
IPR036770
Domain description: Ankyrin repeat-containing domain superfamily
Occurring in:
  1. Transient receptor potential cation channel subfamily A member 1
IPR005821
Domain description: Ion transport domain
Occurring in:
  1. Transient receptor potential cation channel subfamily A member 1

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