6wkl

X-ray diffraction
1.89Å resolution

Fab Fragment of Anti-human LAG3 antibody (BAP050)

Released:
Source organism: Mus musculus
Entry authors: Agnihotri P, Mishra AK, Mariuzza RA

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-214264 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
BAP050 Fab Heavy Chain Chain: A
Molecule details ›
Chain: A
Length: 241 amino acids
Theoretical weight: 25.86 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
BAP050 Fab Light Chain Chain: B
Molecule details ›
Chain: B
Length: 214 amino acids
Theoretical weight: 23.7 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 67.77Å b: 75.53Å c: 103.06Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.193 0.223
Expression system: Homo sapiens