6wpt

Electron Microscopy
3.7Å resolution

Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment (open state)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
PDBe Complex ID:
PDB-CPX-279706 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (6 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1281 amino acids
Theoretical weight: 141.53 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
S309 neutralizing antibody heavy chain Chains: D, H
Molecule details ›
Chains: D, H
Length: 127 amino acids
Theoretical weight: 14.01 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
S309 neutralizing antibody light chain Chains: E, L

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, FUC
Carbohydrate polymer : NEW Components: NAG, BMA, FUC, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-21865
Expression system: Homo sapiens