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Structure of human Frizzled5 by fiducial-assisted cryo-EM

Source organisms:
Biochemical function: metal ion binding
Biological process: electron transport chain
Cellular component: periplasmic space

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF07361
Domain description: Cytochrome b562
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
The deposited structure of PDB entry 6ww2 contains 1 copy of Pfam domain PF07361 (Cytochrome b562) in Frizzled-5. Showing 1 copy in chain D [auth R].

PF01534
Domain description: Frizzled/Smoothened family membrane region
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
The deposited structure of PDB entry 6ww2 contains 1 copy of Pfam domain PF01534 (Frizzled/Smoothened family membrane region) in Frizzled-5. Showing 1 copy in chain D [auth R].

PF01392
Domain description: Fz domain
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
The deposited structure of PDB entry 6ww2 contains 1 copy of Pfam domain PF01392 (Fz domain) in Frizzled-5. Showing 1 copy in chain D [auth R] (this domain is out of the observed residue ranges!).

InterPro InterPro annotations
IPR000539
Domain description: Frizzled/Smoothened, 7TM
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. anti-BRIL Fab Heavy chain
  2. anti-Fab Nanobody
  3. anti-BRIL Fab Light chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. anti-BRIL Fab Heavy chain
  2. anti-Fab Nanobody
  3. anti-BRIL Fab Light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. anti-BRIL Fab Heavy chain
  2. anti-Fab Nanobody
  3. anti-BRIL Fab Light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. anti-BRIL Fab Heavy chain
  2. anti-Fab Nanobody
  3. anti-BRIL Fab Light chain
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. anti-BRIL Fab Heavy chain
  2. anti-BRIL Fab Light chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. anti-BRIL Fab Heavy chain
  2. anti-Fab Nanobody
  3. anti-BRIL Fab Light chain
IPR020067
Domain description: Frizzled domain
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
IPR036790
Domain description: Frizzled cysteine-rich domain superfamily
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. anti-BRIL Fab Heavy chain
  2. anti-BRIL Fab Light chain
IPR009155
Domain description: Cytochrome b562
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
IPR010980
Domain description: Cytochrome c/b562
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
IPR017981
Domain description: GPCR, family 2-like, 7TM
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
IPR015526
Domain description: Frizzled/secreted frizzled-related protein
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562
IPR037441
Domain description: Frizzled-5, CRD domain
Occurring in:
  1. Frizzled-5; Soluble cytochrome b562

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