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Electron Microscopy
3.34Å resolution

Cryo-EM structure of the human chemokine receptor CCR6 in complex with CCL20 and a Go protein

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-209407 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B
Molecule details ›
Chain: B
Length: 351 amino acids
Theoretical weight: 38.74 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
C-C motif chemokine 20 Chain: C
Molecule details ›
Chain: C
Length: 70 amino acids
Theoretical weight: 8.04 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: Y
Guanine nucleotide-binding protein G(o) subunit alpha Chain: A
scFv16 Chain: S
C-C chemokine receptor type 6; Soluble cytochrome b562 Chain: R

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.34Å
Relevant EMDB volumes: EMD-21950
Expression system: Spodoptera frugiperda