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Asymmetric model of CD4-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52

Source organisms:
Biochemical function: structural molecule activity
Biological process: cell adhesion
Cellular component: membrane

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF05790
Domain description: Immunoglobulin C2-set domain
Occurring in:
  1. T-cell surface glycoprotein CD4
The deposited structure of PDB entry 6x5c contains 3 copies of Pfam domain PF05790 (Immunoglobulin C2-set domain) in T-cell surface glycoprotein CD4. Showing 1 copy in chain C (this domain is out of the observed residue ranges!).

PF00047
Domain description: Immunoglobulin domain
Occurring in:
  1. T-cell surface glycoprotein CD4
The deposited structure of PDB entry 6x5c contains 3 copies of Pfam domain PF00047 (Immunoglobulin domain) in T-cell surface glycoprotein CD4. Showing 1 copy in chain C.

PF00517
Domain description: Retroviral envelope protein
Occurring in:
  1. Transmembrane protein gp41
The deposited structure of PDB entry 6x5c contains 3 copies of Pfam domain PF00517 (Retroviral envelope protein) in Transmembrane protein gp41. Showing 1 copy in chain B.

PF00516
Domain description: Envelope glycoprotein GP120
Occurring in:
  1. Envelope glycoprotein gp160
The deposited structure of PDB entry 6x5c contains 3 copies of Pfam domain PF00516 (Envelope glycoprotein GP120) in Envelope glycoprotein gp160. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR036377
Domain description: Gp120 core superfamily
Occurring in:
  1. Envelope glycoprotein gp160
IPR003598
Domain description: Immunoglobulin subtype 2
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR000328
Domain description: Retroviral envelope protein GP41-like
Occurring in:
  1. Transmembrane protein gp41
IPR008424
Domain description: Immunoglobulin C2-set
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR013151
Domain description: Immunoglobulin-like beta-sandwich domain
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. T-cell surface glycoprotein CD4
IPR000777
Domain description: Human immunodeficiency virus 1, envelope glycoprotein Gp120
Occurring in:
  1. Envelope glycoprotein gp160

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