6x65

Electron Microscopy
3.7Å resolution

Legionella pneumophila Dot/Icm T4SS

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 153-mer (preferred)
PDBe Complex ID:
PDB-CPX-235714 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Type IV secretion system unknown protein fragment Chains: AV, AW, AX, AY, AZ, BV, BW, BX, BY, BZ, CV, CW, CX, CY, CZ, DV, DW, DX, DY, DZ, EV, EW, EX, EY, EZ, FV, FW, FX, FY, FZ, GV, GW, GX, GY, GZ, HV, HW, HX, HY, HZ, IV, IW, IX, IY, IZ, JV, JW, JX, JY, JZ, KV, KW, KX, KY, KZ, LV, LW, LX, LY, LZ, MV, MW, MX, MY, MZ, NV, NW, OV, OW, PV, PW, QV, QW, RV, RW
Molecule details ›
Chains: AV, AW, AX, AY, AZ, BV, BW, BX, BY, BZ, CV, CW, CX, CY, CZ, DV, DW, DX, DY, DZ, EV, EW, EX, EY, EZ, FV, FW, FX, FY, FZ, GV, GW, GX, GY, GZ, HV, HW, HX, HY, HZ, IV, IW, IX, IY, IZ, JV, JW, JX, JY, JZ, KV, KW, KX, KY, KZ, LV, LW, LX, LY, LZ, MV, MW, MX, MY, MZ, NV, NW, OV, OW, PV, PW, QV, QW, RV, RW
Length: 228 amino acids
Theoretical weight: 19.42 KDa
Source organism: Legionella pneumophila
Type IV secretion system DotC family protein Chains: AC, BC, CC, DC, EC, FC, GC, HC, IC, JC, KC, LC, MC
Molecule details ›
Chains: AC, BC, CC, DC, EC, FC, GC, HC, IC, JC, KC, LC, MC
Length: 303 amino acids
Theoretical weight: 34.16 KDa
Source organism: Legionella pneumophila
UniProt:
  • Canonical: O52184 (Residues: 1-303; Coverage: 100%)
Gene names: C3928_14230, F7Z80_08005, F9V49_09090, I8572_002175, I8Y58_002455, I8Z60_002260, JBJ86_00865, KLD42_000197, dotC
Sequence domains: Type IV secretory system, conjugal DNA-protein transfer
Type IVB secretion system lipoprotein DotD Chains: AD, Ad, BD, Bd, CD, Cd, DD, Dd, ED, Ed, FD, Fd, GD, Gd, HD, Hd, ID, Id, JD, Jd, KD, Kd, LD, Ld, MD, Md
Molecule details ›
Chains: AD, Ad, BD, Bd, CD, Cd, DD, Dd, ED, Ed, FD, Fd, GD, Gd, HD, Hd, ID, Id, JD, Jd, KD, Kd, LD, Ld, MD, Md
Length: 163 amino acids
Theoretical weight: 17.86 KDa
Source organism: Legionella pneumophila
UniProt:
  • Canonical: O52183 (Residues: 1-163; Coverage: 100%)
Gene names: DIZ50_08440, JBJ86_00860, JBK99_04205, dotD
Sequence domains: DotD protein
Type IV secretion protein IcmK Chains: AH, BH, CH, DH, EH, FH, GH, HH, IH, JH, KH, LH, MH
Molecule details ›
Chains: AH, BH, CH, DH, EH, FH, GH, HH, IH, JH, KH, LH, MH
Length: 361 amino acids
Theoretical weight: 38.96 KDa
Source organism: Legionella pneumophila
OmpA-like domain-containing protein Chains: AK, BK, CK, DK, EK, FK, GK, HK, IK, JK, KK, LK, MK
Molecule details ›
Chains: AK, BK, CK, DK, EK, FK, GK, HK, IK, JK, KK, LK, MK
Length: 189 amino acids
Theoretical weight: 21.1 KDa
Source organism: Legionella pneumophila
UniProt:
  • Canonical: O53086 (Residues: 1-189; Coverage: 100%)
Gene names: DIZ50_13040, ERS253263_00465, JBJ86_08710, JBK99_08030, NCTC12000_00581, O6C86_13655, icmN, lphA, yiaD_1
Sequence domains: OmpA family
OmpA-like domain-containing protein Chains: N, O, P, Q, R, S, T, U, V, W, X, Y, Z
Molecule details ›
Chains: N, O, P, Q, R, S, T, U, V, W, X, Y, Z
Length: 249 amino acids
Theoretical weight: 27.58 KDa
Source organism: Legionella pneumophila
UniProt:
  • Canonical: Q5ZXS4 (Residues: 1-249; Coverage: 100%)
Gene name: lpg0657
Sequence domains: OmpA family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-22070