› 6x6w

X-ray diffraction
1.89Å resolution

Crystal structure of inactive enzymatic binary toxin component from Clostridium difficile

Released:
DOI: 10.2210/pdb6x6w/pdb
PDB entry 6x6w coloured by chain, front view.
PDB entry 6x6w coloured by chain, side view.
PDB entry 6x6w coloured by chain, top view.
Source organism: Clostridioides difficile
Entry author: Pozharski E

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191885 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP ribosyltransferase domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 420 amino acids
Theoretical weight: 48.28 KDa
Source organism: Clostridioides difficile
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9KH42 (Residues: 44-463; Coverage: 91%)
Gene name: cdtA
Sequence domains: ADP-ribosyltransferase exoenzyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P21
Unit cell:
a: 77.24Å b: 44.47Å c: 78.39Å
α: 90° β: 116.96° γ: 90°
R-values:
R R work R free
0.194 0.192 0.226
Expression system: Escherichia coli

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