› 6xhh

X-ray diffraction
1.5Å resolution

Far-red absorbing dark state of JSC1_58120g3 with bound 18-1, 18-2 dihydrobiliverdin IXa (DHBV), the native chromophore precursor

Released:
DOI: 10.2210/pdb6xhh/pdb
PDB entry 6xhh coloured by chain, front view.
PDB entry 6xhh coloured by chain, side view.
PDB entry 6xhh coloured by chain, top view.
Source organism: [Leptolyngbya] sp. JSC-1
Primary publication:
A far-red cyanobacteriochrome lineage specific for verdins.
Moreno MV, Rockwell NC, Mora M, Fisher AJ, Lagarias JC
Proc Natl Acad Sci U S A 117 27962-27970 (2020)
PMID: 33106421

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167772 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
JSC1_58120g3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 182 amino acids
Theoretical weight: 21.03 KDa
Source organism: [Leptolyngbya] sp. JSC-1
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
Ligand M1V 2 x M1V
Ligand EDO 8 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P1
Unit cell:
a: 32.286Å b: 35.814Å c: 74.875Å
α: 100.19° β: 95.37° γ: 89.86°
R-values:
R R work R free
0.196 0.194 0.231
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Red Light Optogenetics in Neuroscience.
Lehtinen et al. (2021)
3 more

2 mentions without citation

A far-red cyanobacteriochrome lineage specific for verdins.
Moreno et al. (2020)
1 more