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Nitric Oxide Synthase from Bacillus subtilis in complex with 7-((3-(((4-(6-aminopyridin-2-yl)butyl)amino)methyl)phenoxy)methyl)quinolin-2-amine

Source organism: Bacillus subtilis subsp. subtilis str. 168
Biochemical function: metal ion binding
Biological process: nitric oxide biosynthetic process
Cellular component: cellular_component

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EC 1.14.14.47: Nitric-oxide synthase (flavodoxin)

Reaction catalysed:
(1a) 2 L-arginine + 2 reduced flavodoxin + 2 O(2) = 2 N(omega)-hydroxy-L-arginine + 2 oxidized flavodoxin + 2 H(2)O
Systematic name:
L-arginine,reduced-flavodoxin:oxygen oxidoreductase (nitric-oxide-forming)
Alternative Name(s):
  • NO synthase
  • Nitric oxide synthetase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF02898
Domain description: Nitric oxide synthase, oxygenase domain
Occurring in:
  1. Nitric oxide synthase oxygenase
The deposited structure of PDB entry 6xk5 contains 1 copy of Pfam domain PF02898 (Nitric oxide synthase, oxygenase domain) in Nitric oxide synthase oxygenase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR004030
Domain description: Nitric oxide synthase, N-terminal
Occurring in:
  1. Nitric oxide synthase oxygenase
IPR044944
Domain description: Nitric oxide synthase, domain 3 superfamily
Occurring in:
  1. Nitric oxide synthase oxygenase
IPR044940
Domain description: Nitric oxide synthase, domain 2 superfamily
Occurring in:
  1. Nitric oxide synthase oxygenase
IPR044943
Domain description: Nitric oxide synthase, domain 1 superfamily
Occurring in:
  1. Nitric oxide synthase oxygenase
IPR036119
Domain description: Nitric oxide synthase, N-terminal domain superfamily
Occurring in:
  1. Nitric oxide synthase oxygenase
IPR017142
Domain description: Nitric oxide synthase, oxygenase subunit
Occurring in:
  1. Nitric oxide synthase oxygenase

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