› 6xl7

X-ray diffraction
1.42Å resolution

Structure of a mosquito complement inhibitor from Anopheles freeborni

Released:
DOI: 10.2210/pdb6xl7/pdb
PDB entry 6xl7 coloured by chain, front view.
PDB entry 6xl7 coloured by chain, side view.
PDB entry 6xl7 coloured by chain, top view.
Source organism: Anopheles freeborni
Primary publication:
Salivary complement inhibitors from mosquitoes: Structure and mechanism of action.
Strayer EC, Lu S, Ribeiro J, Andersen JF
OpenAccess logo J Biol Chem 296 100083
PMID: 33199367

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167785 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SG7.AF Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.84 KDa
Source organism: Anopheles freeborni
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

2 bound ligands:
Ligand SO4 4 x SO4
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P41212
Unit cell:
a: 85.98Å b: 85.98Å c: 46.08Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.193
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Arboviruses: How Saliva Impacts the Journey from Vector to Host.
Schneider et al. (2021)
2 other articles

2 mentions without citation

Salivary complement inhibitors from mosquitoes: Structure and mechanism of action.
Strayer et al. (2021)
1 more