› 6xlf

Electron Microscopy
3.15Å resolution

Full-length Hsc82 in complex with Aha1 in the presence of AMP-PNP

Released:
DOI: 10.2210/pdb6xlf/pdb
PDB entry 6xlf coloured by chain, front view.
PDB entry 6xlf coloured by chain, side view.
PDB entry 6xlf coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Entry authors: Liu YX, Sun M, Myasnikov AG, Elnatan D, Agard DA
Related structures: EMD-22242

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-537843 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ATP-dependent molecular chaperone HSC82 Chains: A, B
Molecule details ›
Chains: A, B
Length: 705 amino acids
Theoretical weight: 81 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P15108 (Residues: 1-705; Coverage: 100%)
Gene names: HSC82, YM8010.16, YMR186W
Sequence domains:
Hsp90 co-chaperone AHA1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 350 amino acids
Theoretical weight: 39.49 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12449 (Residues: 1-350; Coverage: 100%)
Gene names: AHA1, YD8142.16, YD8142B.06, YDR214W
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand ANP 2 x ANP
Ligand MG 2 x MG
Ligand K 2 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.15Å
Relevant EMDB volumes: EMD-22242
Expression system: Escherichia coli

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