Function and Biology

Full-length Hsc82 in complex with Aha1 in the presence of AMP-PNP

Source organism: Saccharomyces cerevisiae S288C
Biochemical function: protein binding
Biological process: protein folding
Cellular component: cytosol

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF08327
Domain description: Activator of Hsp90 ATPase homolog 1-like protein
Occurring in:
  1. Hsp90 co-chaperone AHA1
The deposited structure of PDB entry 6xlf contains 2 copies of Pfam domain PF08327 (Activator of Hsp90 ATPase homolog 1-like protein) in Hsp90 co-chaperone AHA1. Showing 1 copy in chain C.

PF09229
Domain description: Activator of Hsp90 ATPase, N-terminal
Occurring in:
  1. Hsp90 co-chaperone AHA1
The deposited structure of PDB entry 6xlf contains 2 copies of Pfam domain PF09229 (Activator of Hsp90 ATPase, N-terminal) in Hsp90 co-chaperone AHA1. Showing 1 copy in chain C.

PF00183
Domain description: Hsp90 protein
Occurring in:
  1. ATP-dependent molecular chaperone HSC82
The deposited structure of PDB entry 6xlf contains 2 copies of Pfam domain PF00183 (Hsp90 protein) in ATP-dependent molecular chaperone HSC82. Showing 1 copy in chain B.

PF13589
Domain description: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Occurring in:
  1. ATP-dependent molecular chaperone HSC82
The deposited structure of PDB entry 6xlf contains 2 copies of Pfam domain PF13589 (Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase) in ATP-dependent molecular chaperone HSC82. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR020575
Domain description: Heat shock protein Hsp90, N-terminal
Occurring in:
  1. ATP-dependent molecular chaperone HSC82
IPR001404
Domain description: Heat shock protein Hsp90 family
Occurring in:
  1. ATP-dependent molecular chaperone HSC82
IPR015310
Domain description: Activator of Hsp90 ATPase AHSA1-like, N-terminal
Occurring in:
  1. Hsp90 co-chaperone AHA1
IPR036338
Domain description: Activator of Hsp90 ATPase, Aha1
Occurring in:
  1. Hsp90 co-chaperone AHA1
IPR037196
Domain description: HSP90, C-terminal domain
Occurring in:
  1. ATP-dependent molecular chaperone HSC82
IPR003594
Domain description: Histidine kinase/HSP90-like ATPase domain
Occurring in:
  1. ATP-dependent molecular chaperone HSC82
IPR036890
Domain description: Histidine kinase/HSP90-like ATPase superfamily
Occurring in:
  1. ATP-dependent molecular chaperone HSC82
IPR013538
Domain description: Activator of Hsp90 ATPase homologue 1/2-like, C-terminal
Occurring in:
  1. Hsp90 co-chaperone AHA1
IPR023393
Domain description: START-like domain superfamily
Occurring in:
  1. Hsp90 co-chaperone AHA1
IPR020568
Domain description: Ribosomal protein uS5 domain 2-type superfamily
Occurring in:
  1. ATP-dependent molecular chaperone HSC82
IPR019805
Domain description: Heat shock protein Hsp90, conserved site
Occurring in:
  1. ATP-dependent molecular chaperone HSC82