6xos

Electron Microscopy
3.7Å resolution

CryoEM structure of human presequence protease in partial open state 1

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-177328 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Presequence protease, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 1014 amino acids
Theoretical weight: 114.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q5JRX3 (Residues: 33-1037; Coverage: 97%)
  • Best match: Q5JRX3-2 (Residues: 33-1038)
Gene names: KIAA1104, MP1, PITRM1, PREP
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-22278
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'