› 6xr2

X-ray diffraction
3.2Å resolution

Computationally designed right-handed alpha/alpha homotrimeric toroid with 3 repeats per subunit

Released:
DOI: 10.2210/pdb6xr2/pdb
PDB entry 6xr2 coloured by chain, front view.
PDB entry 6xr2 coloured by chain, side view.
PDB entry 6xr2 coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces.
Hallinan JP, Doyle LA, Shen BW, Gewe MM, Takushi B, Kennedy MA, Friend D, Roberts JM, Bradley P, Stoddard BL
OpenAccess logo Commun Biol 4 1240 (2021)
PMID: 34716407

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167792 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dTor_3x57R Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 172 amino acids
Theoretical weight: 18.95 KDa
Source organism: synthetic construct
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P21
Unit cell:
a: 57.647Å b: 78.93Å c: 112.694Å
α: 90° β: 93.82° γ: 90°
R-values:
R R work R free
0.251 0.243 0.329
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Design of stimulus-responsive two-state hinge proteins.
Praetorius et al. (2023)
2 more

1 mention without citation

Stepwise design of pseudosymmetric protein hetero-oligomers.
Kibler et al. (2023)