› 6xy1

X-ray diffraction
1.5Å resolution

Crystal structure of a de novo designed parallel four-helix coiled coil, 4-KE-4.

Released:
DOI: 10.2210/pdb6xy1/pdb
PDB entry 6xy1 coloured by chain, front view.
PDB entry 6xy1 coloured by chain, side view.
PDB entry 6xy1 coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Robust De Novo-Designed Homotetrameric Coiled Coils.
Edgell CL, Savery NJ, Woolfson DN
Biochemistry 59 1087-1092 (2020)
PMID: 32133841

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167810 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
4-KE-4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 32 amino acids
Theoretical weight: 3.69 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P43
Unit cell:
a: 53.52Å b: 53.52Å c: 50.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.161 0.188
Expression system: Not provided

Quick links

Citations

1 review citation

Recent Progress Using De Novo Design to Study Protein Structure, Design and Binding Interactions.
Ferrando et al. (2021)
5 other articles

1 mention without citation

Understanding a protein fold: The physics, chemistry, and biology of α-helical coiled coils.
Woolfson DN. (2023)