› 6y1s

X-ray diffraction
1.04Å resolution

Bicyclic peptide bp70 in I4132 at 1.0 Angstrom resolution

Released:
DOI: 10.2210/pdb6y1s/pdb
PDB entry 6y1s coloured by chain, front view.
PDB entry 6y1s coloured by chain, side view.
PDB entry 6y1s coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
A mixed chirality α-helix in a stapled bicyclic and a linear antimicrobial peptide revealed by X-ray crystallography.
Baeriswyl S, Personne H, Di Bonaventura I, Köhler T, van Delden C, Stocker A, Javor S, Reymond JL
OpenAccess logo RSC Chem Biol 2 1608-1617 (2021)
PMID: 34977576

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167827 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
bp70 Chain: A
Molecule details ›
Chain: A
Length: 13 amino acids
Theoretical weight: 1.53 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
3 modified residues:
Ligand ORN 1 x ORN
Ligand NLE 1 x NLE
Ligand DAB 1 x DAB

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: I4132
Unit cell:
a: 55.459Å b: 55.459Å c: 55.459Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
not available not available 0.234
Expression system: Not provided

Quick links

Citations

5 citation in other articles

Machine Learning Guided Discovery of Non-Hemolytic Membrane Disruptive Anticancer Peptides.
Zakharova et al. (2022)
4 more

1 mention without citation

A mixed chirality α-helix in a stapled bicyclic and a linear antimicrobial peptide revealed by X-ray crystallography.
Baeriswyl et al. (2021)