6y38

X-ray diffraction
1.7Å resolution

Crystal structure of Whirlin PDZ3 in complex with Myosin 15a C-terminal PDZ binding motif peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-182386 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Whirlin Chains: A, B
Molecule details ›
Chains: A, B
Length: 102 amino acids
Theoretical weight: 11.02 KDa
Source organism: Mus musculus
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q80VW5 (Residues: 821-915; Coverage: 10%)
Gene names: Dfnb31, Kiaa1526, Whrn
Sequence domains: PDZ domain
Unconventional myosin-XV Chains: C, D
Molecule details ›
Chains: C, D
Length: 13 amino acids
Theoretical weight: 1.48 KDa
Source organism: Mus musculus
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q9QZZ4 (Residues: 3499-3511; Coverage: 0%)
Gene names: Myo15, Myo15a

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P21212
Unit cell:
a: 54.14Å b: 112.92Å c: 34.63Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.207 0.231
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'