› 6y3h

Solution NMR

NMR solution structure of the hazelnut allergen Cor a 1.0401

Released:
DOI: 10.2210/pdb6y3h/pdb
PDB entry 6y3h coloured by chain, ensemble of 20 models, front view.
PDB entry 6y3h coloured by chain, ensemble of 20 models, side view.
PDB entry 6y3h coloured by chain, ensemble of 20 models, top view.
Source organism: Corylus avellana
Primary publication:
Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens.
Führer S, Kamenik AS, Zeindl R, Nothegger B, Hofer F, Reider N, Liedl KR, Tollinger M
OpenAccess logo Sci Rep 11 4173 (2021)
PMID: 33603065

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193554 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bet v I/Major latex protein domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 160 amino acids
Theoretical weight: 17.47 KDa
Source organism: Corylus avellana
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9SWR4 (Residues: 2-161; Coverage: 99%)
Gene name: CORA1.0401
Sequence domains: Pathogenesis-related protein Bet v 1 family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

A systematic review of allergen cross-reactivity: Translating basic concepts into clinical relevance.
Sharma et al. (2024)
7 other articles

3 mentions without citation

The History and Science of the Major Birch Pollen Allergen Bet v 1.
Breiteneder et al. (2023)
2 more