› 6yi3

Solution NMR

The N-terminal RNA-binding domain of the SARS-CoV-2 nucleocapsid phosphoprotein

Released:
DOI: 10.2210/pdb6yi3/pdb
PDB entry 6yi3 coloured by chain, ensemble of 40 models, front view.
PDB entry 6yi3 coloured by chain, ensemble of 40 models, side view.
PDB entry 6yi3 coloured by chain, ensemble of 40 models, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein.
Dinesh DC, Chalupska D, Silhan J, Koutna E, Nencka R, Veverka V, Boura E
OpenAccess logo PLoS Pathog 16 e1009100 (2020)
PMID: 33264373

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144998 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 15.13 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DTC9 (Residues: 44-180; Coverage: 33%)
Gene name: N
Sequence domains: Coronavirus nucleocapsid

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

22 review citations

Structural insights into SARS-CoV-2 proteins.
Arya et al. (2021)
21 more

54 mentions without citation

The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral Structure, Biological Functions, and a Potential Target for Drug or Vaccine Mitigation.
Bai et al. (2021)
53 more