› 6yr3

X-ray diffraction
1.48Å resolution

1.48 Angstrom Resolution Crystal Structure of Transaldolase from Thermoplasma acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate

Released:
DOI: 10.2210/pdb6yr3/pdb
PDB entry 6yr3 coloured by chain, front view.
PDB entry 6yr3 coloured by chain, side view.
PDB entry 6yr3 coloured by chain, top view.
Source organism: Thermoplasma acidophilum DSM 1728
Entry authors: Sautner V, Tittmann K

Function and Biology Details

Reaction catalysed: 
Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190875 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable transaldolase Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 223 amino acids
Theoretical weight: 24.49 KDa
Source organism: Thermoplasma acidophilum DSM 1728
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HKI3 (Residues: 1-223; Coverage: 100%)
Gene names: Ta0616, tal
Sequence domains: Transaldolase/Fructose-6-phosphate aldolase

Ligands and Environments

3 bound ligands:
Ligand F6R 5 x F6R
Ligand GOL 5 x GOL
Ligand ACT 6 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup: C2221
Unit cell:
a: 148.51Å b: 172.2Å c: 100.58Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.16 0.186
Expression system: Escherichia coli BL21(DE3)

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