6yup

Electron Microscopy
2.9Å resolution

Heterotetrameric structure of the rBAT-b(0,+)AT1 complex

Released:
Source organism: Homo sapiens
Primary publication:
Structural basis for amino acid exchange by a human heteromeric amino acid transporter.
Proc Natl Acad Sci U S A 117 21281-21287 (2020)
PMID: 32817565
Related structures: EMD-10933

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-160616 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Amino acid transporter heavy chain SLC3A1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 685 amino acids
Theoretical weight: 78.94 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q07837 (Residues: 1-685; Coverage: 100%)
Gene names: NBAT, SLC3A1
Sequence domains: Alpha amylase, catalytic domain
b(0,+)-type amino acid transporter 1 Chains: D, E
Molecule details ›
Chains: D, E
Length: 487 amino acids
Theoretical weight: 53.52 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P82251 (Residues: 1-487; Coverage: 100%)
Gene names: BAT1, SLC7A9
Sequence domains: Amino acid permease

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.9Å
Relevant EMDB volumes: EMD-10933
Expression system: Homo sapiens