› 6yza

X-ray diffraction
1.3Å resolution

Trypsin inhibitor in complex with bovine trypsin

Released:
DOI: 10.2210/pdb6yza/pdb
PDB entry 6yza coloured by chain, front view.
PDB entry 6yza coloured by chain, side view.
PDB entry 6yza coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Badran MJ, Heine A, Klebe G

Function and Biology Details

Reaction catalysed: 
Preferential cleavage: Arg-|-, Lys-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133319 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine protease 1 Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Gene names: PRSS1, TRP1, TRY1, TRYP1
Sequence domains: Trypsin

Ligands and Environments

4 bound ligands:
Ligand CA 1 x CA
Ligand TP5 1 x TP5
Ligand SO4 1 x SO4
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P3121
Unit cell:
a: 54.739Å b: 54.739Å c: 107.104Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.152 0.151 0.173

Quick links