6z1p

Electron Microscopy
3.7Å resolution

Structure of the mitochondrial ribosome from Tetrahymena thermophila

Released:

Function and Biology Details

Reactions catalysed:
3-hydroxy-2-methylpropanoyl-CoA + H(2)O = CoA + 3-hydroxy-2-methylpropanoate
Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 99-mer (preferred)
PDBe Complex ID:
PDB-CPX-107437 (preferred)
Entry contents:
95 distinct polypeptide molecules
4 distinct RNA molecules
Macromolecules (99 distinct):
Large ribosomal subunit protein uL2 C-terminal domain-containing protein Chain: Ac
Molecule details ›
Chain: Ac
Length: 262 amino acids
Theoretical weight: 29.97 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951B6 (Residues: 1-262; Coverage: 100%)
Gene name: rpl2
Sequence domains: Ribosomal Proteins L2, C-terminal domain
Large ribosomal subunit protein uL3m Chain: Ad
Molecule details ›
Chain: Ad
Length: 439 amino acids
Theoretical weight: 49.88 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22HG3 (Residues: 1-439; Coverage: 100%)
Gene name: TTHERM_00637400
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4m Chain: Ae
Ymf69 Chain: Af
Ymf60 Chain: Ag
bL7/L12m Chain: Ah
bL7/12m Chain: Ai
bL7/12m Chain: Aj
Large ribosomal subunit protein bL12 C-terminal domain-containing protein Chain: Ak
Ribosomal protein L9 domain-containing protein Chain: Al
Ymf74 Chain: Am
Ribosomal protein L11, amine-terminal domain protein Chain: An
50S ribosomal protein L13 Chain: Ao
Ribosomal protein L14 Chain: Ap
Large ribosomal subunit protein uL15/eL18 domain-containing protein Chain: Aq
Ribosomal protein L16 Chain: Ar
50S ribosomal protein L17 Chain: As
Ribosomal protein L19 Chain: At
50S ribosomal protein L20 Chain: Au
Large ribosomal subunit protein bL21m Chain: Av
Ribosomal protein L22/L17e Chain: Aw
Large ribosomal subunit protein uL23m Chain: Ax
Large ribosomal subunit protein uL24c Chain: Ay
bL25m Chain: Az
50S ribosomal protein L27 Chain: AA
Ribosomal protein L28 Chain: AB
Large ribosomal subunit protein uL29m Chain: AC
bL32m Chain: AD
50S ribosomal protein L33 Chain: AE
50S ribosomal protein L35 Chain: AF
Ribosomal protein Chain: AG
mL40 Chain: AH
Ribosomal protein L27 Chain: AI
Large ribosomal subunit protein mL43 Chain: AJ
39S ribosomal protein L46, mitochondrial Chain: AK
Large ribosomal subunit protein mL49 Chain: AL
mL53 Chain: AM
mL54 Chain: AN
mL64 Chain: AO
mL101 Chain: AP
mL102 Chain: AQ
mL103 Chain: AR
mL104 Chain: AS
Signal recognition particle SRP54 subunit M-domain domain-containing protein Chain: AT
mL106 Chain: AU
Iron-binding zinc finger CDGSH type domain-containing protein Chain: AV
Ymf73 Chain: Bc
Ymf64 Chain: Bd
Ymf76 Chain: Be
S5 DRBM domain-containing protein Chain: Bf
Ribosomal protein S6 Chain: Bg
Ymf63 Chain: Bh
Ribosomal protein S9 Chain: Bi
Ymf59 Chain: Bj
Ymf61 Chain: Bk
Ribosomal protein S12 Chain: Bl
Ribosomal protein S13 Chain: Bm
Ribosomal protein S14 Chain: Bn
30S ribosomal protein S15 Chain: Bo
30S ribosomal protein S16 Chain: Bp
30S ribosomal protein S17 Chain: Bq
Ribosomal protein S18 Chain: Br
Ribosomal protein S19 Chain: Bs
bS21m Chain: Bt
mS23 Chain: Bu
mS26 Chain: Bv
Small ribosomal subunit protein mS29 Chain: Bw
mS31 Chain: Bx
mS33 Chain: By
mS34 Chain: Bz
Small ribosomal subunit protein mS35 mitochondrial conserved domain-containing protein Chain: BA
mS37 Chain: BB
mS38 Chain: BC
Small ribosomal subunit protein mS41 Chain: BD
mS45 Chain: BE
mS75 Chain: BF
mS76 Chain: BG
mS77 Chain: BH
3-hydroxyisobutyryl-CoA hydrolase Chain: BI
mS78 Chain: BJ
mS79 Chain: BK
peptide-methionine (R)-S-oxide reductase Chain: BL
mS81 Chain: BM
EF-hand domain-containing protein Chain: BN
PARP alpha-helical domain-containing protein Chain: BO
mS84,mS84 Chain: BP
RRM domain-containing protein Chain: BQ
Iron donor protein CyaY Chain: BR
mS87 Chain: BS
mS88 Chain: BT
mS89 Chain: BU
mS90 Chain: BV
mS91 Chain: BW
Ribosomal protein S3 Chain: BX
mTERF protein Chain: BY
LSU rRNA_1 Chain: Aa
LSU rRNA_2 Chain: Ab
SSU rRNA_1 Chain: Ba
SSU rRNA_2 Chain: Bb

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-11032