6z2p

X-ray diffraction
2.16Å resolution

Crystal structure of catalytic inactive OgpA from Akkermansia muciniphila in complex with an O-glycopeptide (glycodrosocin) substrate

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-109751 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Peptidase M43 pregnancy-associated plasma-A domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 371 amino acids
Theoretical weight: 41.73 KDa
Source organism: Akkermansia muciniphila ATCC BAA-835
Expression system: Escherichia coli
UniProt:
  • Canonical: B2UR60 (Residues: 25-385; Coverage: 100%)
Gene name: Amuc_1119
Drosocin Chain: C
Molecule details ›
Chain: C
Length: 19 amino acids
Theoretical weight: 2.2 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P36193 (Residues: 22-40; Coverage: 42%)
Gene names: CG10816, Dro

Ligands and Environments

Carbohydrate polymer : NEW Components: A2G, GAL
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: I4
Unit cell:
a: 126.92Å b: 126.92Å c: 65.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.199 0.232
Expression systems:
  • Escherichia coli
  • Not provided