6z8l

X-ray diffraction
1.4Å resolution

Alpha-Amylase in complex with probe fragments

Released:
Model geometry
Fit model/data

Function and Biology Details

Reaction catalysed:
Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-138163 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Pancreatic alpha-amylase Chain: A
Molecule details ›
Chain: A
Length: 496 amino acids
Theoretical weight: 55.96 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P04746 (Residues: 16-511; Coverage: 100%)
Gene name: AMY2A
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
3 bound ligands:
1 modified residue:

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 51.873Å b: 73.729Å c: 135.207Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.143 0.142 0.154