› 6z9m

Electron Microscopy
9.1Å resolution

Pseudoatomic model of the pre-fusion conformation of glycoprotein B of Herpes simplex virus 1

Released:
DOI: 10.2210/pdb6z9m/pdb
PDB entry 6z9m coloured by chain, front view.
PDB entry 6z9m coloured by chain, side view.
PDB entry 6z9m coloured by chain, top view.
Source organism: Human alphaherpesvirus 1
Primary publication:
The prefusion structure of herpes simplex virus glycoprotein B.
Vollmer B, Pražák V, Vasishtan D, Jefferys EE, Hernandez-Duran A, Vallbracht M, Klupp BG, Mettenleiter TC, Backovic M, Rey FA, Topf M, Grünewald K
OpenAccess logo Sci Adv 6 (2020)
PMID: 32978151
Related structures: EMD-11123

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139046 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope glycoprotein B Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 904 amino acids
Theoretical weight: 100.38 KDa
Source organism: Human alphaherpesvirus 1
Expression system: Mesocricetus auratus
UniProt:
  • Canonical: P06437 (Residues: 1-904; Coverage: 100%)
Gene names: UL27, gB
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 9.1Å
Relevant EMDB volumes: EMD-11123
Expression system: Mesocricetus auratus

Quick links

Citations

8 review citations

The structural basis of herpesvirus entry.
Connolly et al. (2021)
7 more

9 mentions without citation

Well Put Together-A Guide to Accessorizing with the Herpesvirus gH/gL Complexes.
Gonzalez-Del Pino et al. (2022)
8 more