› 6zbl

Electron Microscopy
3.6Å resolution

Plasmodium falciparum merozoite surface protein 1 dimer, conformation 2

Released:
DOI: 10.2210/pdb6zbl/pdb
PDB entry 6zbl coloured by chain, front view.
PDB entry 6zbl coloured by chain, side view.
PDB entry 6zbl coloured by chain, top view.
Source organism: Plasmodium falciparum
Primary publication:
Structure of the merozoite surface protein 1 from Plasmodium falciparum.
Dijkman PM, Marzluf T, Zhang Y, Chang SS, Helm D, Lanzer M, Bujard H, Kudryashev M
Sci Adv 7 (2021)
PMID: 34078606
Related structures: EMD-11157

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184624 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
p83 subunit Chains: A, C
Molecule details ›
Chains: A, C
Length: 891 amino acids
Theoretical weight: 101.97 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8I0U8 (Residues: 20-910; Coverage: 52%)
Gene names: MSP-1, MSP1, PF3D7_0930300
Merozoite surface protein 1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 792 amino acids
Theoretical weight: 89.62 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8I0U8 (Residues: 911-1702; Coverage: 47%)
Gene names: MSP-1, MSP1, PF3D7_0930300
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-11157
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Plasmodium 6-Cysteine Proteins: Functional Diversity, Transmission-Blocking Antibodies and Structural Scaffolds.
Lyons et al. (2022)
2 more