6zd1

X-ray diffraction
2.47Å resolution

Structure of apo telomerase from Candida Tropicalis

Released:

Function and Biology Details

Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-111512 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomerase reverse transcriptase Chain: A
Molecule details ›
Chain: A
Length: 705 amino acids
Theoretical weight: 82.38 KDa
Source organism: Candida tropicalis MYA-3404
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: C5MCQ7 (Residues: 177-879; Coverage: 80%)
Gene name: CTRG_04008
Sequence domains: Telomerase ribonucleoprotein complex - RNA binding domain

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P41212
Unit cell:
a: 65.798Å b: 65.798Å c: 387.948Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.246 0.284
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'