› 6ziw

X-ray diffraction
2.18Å resolution

The IRAK3 Pseudokinase Domain Bound To ATPgammaS

Released:
DOI: 10.2210/pdb6ziw/pdb
PDB entry 6ziw coloured by chain, front view.
PDB entry 6ziw coloured by chain, side view.
PDB entry 6ziw coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Mathea S, Chatterjee D, Preuss F, Kraemer A, Knapp S

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195326 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-1 receptor-associated kinase 3 Chain: I
Molecule details ›
Chain: I
Length: 316 amino acids
Theoretical weight: 36.48 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9Y616 (Residues: 141-455; Coverage: 53%)
Gene name: IRAK3
Sequence domains: Protein kinase domain

Ligands and Environments

2 bound ligands:
Ligand AGS 1 x AGS
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: I4132
Unit cell:
a: 190.45Å b: 190.45Å c: 190.45Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.216 0.25
Expression system: Spodoptera frugiperda

Quick links