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Extended human uromodulin filament core at 3.5 A resolution

Source organism: Homo sapiens
Biochemical function: calcium ion binding
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF07645
Domain description: Calcium-binding EGF domain
Occurring in:
  1. Uromodulin
The deposited structure of PDB entry 6zya contains 2 copies of Pfam domain PF07645 (Calcium-binding EGF domain) in Uromodulin. Showing 2 copies in chain A (this domain is out of the observed residue ranges!).

PF00100
Domain description: Zona pellucida-like domain
Occurring in:
  1. Uromodulin
The deposited structure of PDB entry 6zya contains 1 copy of Pfam domain PF00100 (Zona pellucida-like domain) in Uromodulin. Showing 1 copy in chain A.

PF12947
Domain description: EGF domain
Occurring in:
  1. Uromodulin
The deposited structure of PDB entry 6zya contains 1 copy of Pfam domain PF12947 (EGF domain) in Uromodulin. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

InterPro InterPro annotations
IPR001507
Domain description: Zona pellucida domain
Occurring in:
  1. Uromodulin
IPR000742
Domain description: EGF-like domain
Occurring in:
  1. Uromodulin
IPR001881
Domain description: EGF-like calcium-binding domain
Occurring in:
  1. Uromodulin
IPR000152
Domain description: EGF-type aspartate/asparagine hydroxylation site
Occurring in:
  1. Uromodulin
IPR024731
Domain description: EGF domain
Occurring in:
  1. Uromodulin
IPR017977
Domain description: Zona pellucida domain, conserved site
Occurring in:
  1. Uromodulin
IPR042235
Domain description: Zona pellucida, ZP-C domain
Occurring in:
  1. Uromodulin
IPR018097
Domain description: EGF-like calcium-binding, conserved site
Occurring in:
  1. Uromodulin
IPR009030
Domain description: Growth factor receptor cysteine-rich domain superfamily
Occurring in:
  1. Uromodulin

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