› 7b1z

X-ray diffraction
1.71Å resolution

Virulence-associated protein VapB from the intracellular pathogen Rhodococcus equi

Released:
DOI: 10.2210/pdb7b1z/pdb
PDB entry 7b1z coloured by chain, front view.
PDB entry 7b1z coloured by chain, side view.
PDB entry 7b1z coloured by chain, top view.
Source organism: Rhodococcus equi
Primary publication:
Conformational changes of loops highlight a potential binding site in Rhodococcus equi VapB.
Geerds C, Haas A, Niemann HH
OpenAccess logo Acta Crystallogr F Struct Biol Commun 77 246-253 (2021)
PMID: 34341190

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-110083 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Virulence associated protein VapB Chains: A, B
Molecule details ›
Chains: A, B
Length: 113 amino acids
Theoretical weight: 12.09 KDa
Source organism: Rhodococcus equi
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B4F366 (Residues: 85-197; Coverage: 69%)
Gene name: pVAPB_vapB
Sequence domains: Rhodococcus equi virulence-associated protein

Ligands and Environments

2 bound ligands:
Ligand GOL 5 x GOL
Ligand NO3 2 x NO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: C2221
Unit cell:
a: 56.94Å b: 65.34Å c: 124.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.155 0.154 0.182
Expression system: Escherichia coli BL21(DE3)

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Citations

1 citations in other articles

Genomic Characteristics Revealed Plasmid-Mediated Pathogenicity and Ubiquitous Rifamycin Resistance of Rhodococcus equi.
Song et al. (2022)

2 mentions without citation

Conformational changes of loops highlight a potential binding site in Rhodococcus equi VapB.
Geerds et al. (2021)
1 more