› 7dk0

X-ray diffraction
3.2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-209734 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
MW05 heavy chain Chain: A
Molecule details ›
Chain: A
Length: 228 amino acids
Theoretical weight: 23.86 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
MW05 light chain Chain: B
Molecule details ›
Chain: B
Length: 213 amino acids
Theoretical weight: 22.96 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Spike protein S1 Chain: C
Molecule details ›
Chain: C
Length: 223 amino acids
Theoretical weight: 25.12 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P0DTC2 (Residues: 319-541; Coverage: 18%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P3221
Unit cell:
a: 87Å b: 87Å c: 216.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.221 0.218 0.265
Expression system: Cricetulus griseus

Quick links

Citations

9 review citations

Dengue and COVID-19: two sides of the same coin.
Malavige et al. (2022)
8 more

5 mentions without citation

Monoclonal antibody therapies against SARS-CoV-2.
Focosi et al. (2022)
4 more