Function and Biology Details
Reaction catalysed:
Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172002 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
Molecule details ›
Chains: A, C
Length: 434 amino acids
Theoretical weight: 49.55 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: 3'5'-cyclic nucleotide phosphodiesterase
Length: 434 amino acids
Theoretical weight: 49.55 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q14432 (Residues: 669-1102; Coverage: 38%)
Sequence domains: 3'5'-cyclic nucleotide phosphodiesterase
Ribonuclease SLFN12
Molecule details ›
Chains: B, D
Length: 567 amino acids
Theoretical weight: 65.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 567 amino acids
Theoretical weight: 65.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q8IYM2 (Residues: 2-568; Coverage: 98%)
Sequence domains:
