PDB 7fu6 experiment details and validation ‹ Protein Data Bank in Europe (PDBe)

Author description:

Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-benzyl-6-(2-chloro-4-methylphenyl)indazole-4-carboxylic acid

Source organism:

Homo sapiens

Expression system:

Escherichia coli BL21(DE3)

Metric	Description
Bond angles in protein, DNA, RNA molecules	0 outlier(s) of 3894 (%)
Bond lengths in protein, DNA, RNA molecules	0 outlier(s) of 2906 (%)
Electron density fit in protein, DNA, RNA molecules	47 outlier(s) of 346 (%)
Ramachandran outliers in protein molecules	9 outlier(s) of 340 (%)
Sidechain rotamer outliers in protein molecules	21 outlier(s) of 321 (%)

SLS BEAMLINE X10SA

Metric	Value	Source
Cell dimensions	a: 162.55 Å b: 44.83 Å c: 59 Å α: 90° β: 90° γ: 90°	Depositor
Number of reflections	18250	Xtriage(Phenix)
Test set size	4.98%	EDS
Data completeness	99.9%	EDS
EDS resolution	2.37Å - 81.27Å	EDS
<I/σ(I)>	1.2	Xtriage(Phenix)
Twinning statistics	<\|L\|> = 0.5 , <L²> = 0.34	Xtriage(Phenix)
Spacegroup	P 2₁ 2₁ 2	Depositor
Possible (pseudo-) translation	The largest off-origin peak in the Patterson function is 5.87% of the height of the origin peak. No significant pseudotranslation is detected.	Xtriage(Phenix)
Wilson B	83 Å²	Xtriage(Phenix)

Protein Data Bank in Europe