7jie

X-ray diffraction
2.25Å resolution

Structure of GII.4 P-domain in Complex with NORO-320 FAB

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-516506 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
VP1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 307 amino acids
Theoretical weight: 34.03 KDa
Source organism: Norovirus Hu/GII.4/Sydney/NSW0514/2012/AU
Expression system: Escherichia coli
UniProt:
  • Canonical: K4LM89 (Residues: 225-531; Coverage: 57%)
Sequence domains: Calicivirus coat protein C-terminal
IgA Fab Heavy Chain Chains: C, E
Molecule details ›
Chains: C, E
Length: 238 amino acids
Theoretical weight: 25.2 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
IgA Fab Light Chain Chains: D, F
Molecule details ›
Chains: D, F
Length: 219 amino acids
Theoretical weight: 23.91 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P21212
Unit cell:
a: 119.254Å b: 186.273Å c: 73.44Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.181 0.225
Expression systems:
  • Escherichia coli
  • Cricetulus griseus