› 7k1s

Electron Microscopy
3.9Å resolution

The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.

Released:
DOI: 10.2210/pdb7k1s/pdb
PDB entry 7k1s coloured by chain, front view.
PDB entry 7k1s coloured by chain, side view.
PDB entry 7k1s coloured by chain, top view.
Source organism: Human alphaherpesvirus 3
Primary publication:
The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.
Oliver SL, Xing Y, Chen DH, Roh SH, Pintilie GD, Bushnell DA, Sommer MH, Yang E, Carfi A, Chiu W, Arvin AM
OpenAccess logo PLoS Pathog 17 e1008961 (2021)
PMID: 33411789
Related structures: EMD-22629

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-492565 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
ORF31 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 931 amino acids
Theoretical weight: 105.47 KDa
Source organism: Human alphaherpesvirus 3
UniProt:
  • Canonical: A0A076N502 (Residues: 1-931; Coverage: 100%)
Gene names: HHV3_gp33, ORF31
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
1 bound ligand:
Ligand NAG 3 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-22629

Quick links

Citations

2 review citations

Varicella-zoster virus: molecular controls of cell fusion-dependent pathogenesis.
Oliver et al. (2020)
1 more

1 mention without citation

The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.
Oliver et al. (2021)