7k9k

Electron Microscopy
3.14Å resolution

SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2H04 (local refinement)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-534809 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike protein S1 Chain: A
Molecule details ›
Chain: A
Length: 195 amino acids
Theoretical weight: 21.87 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 333-527; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
2H04 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 121 amino acids
Theoretical weight: 13.45 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
2H04 light chain Chain: L
Molecule details ›
Chain: L
Length: 106 amino acids
Theoretical weight: 11.46 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.14Å
Relevant EMDB volumes: EMD-22751
Expression system: Homo sapiens