› 7kc9

X-ray diffraction
2.3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-208793 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (6 distinct):
Ricin A chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 267 amino acids
Theoretical weight: 29.94 KDa
Source organism: Ricinus communis
UniProt:
  • Canonical: P02879 (Residues: 36-302; Coverage: 49%)
Sequence domains: Ribosome inactivating protein
Ricin B chain Chains: B, E
Molecule details ›
Chains: B, E
Length: 262 amino acids
Theoretical weight: 28.99 KDa
Source organism: Ricinus communis
UniProt:
  • Canonical: P02879 (Residues: 315-576; Coverage: 48%)
Sequence domains: Ricin-type beta-trefoil lectin domain
VHH antibody V5G1 Chains: C, F
Molecule details ›
Chains: C, F
Length: 130 amino acids
Theoretical weight: 13.88 KDa
Source organism: Vicugna pacos
Expression system: Escherichia coli

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
2 bound ligands:
Ligand ZN 9 x ZN
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P1
Unit cell:
a: 44.345Å b: 77.438Å c: 101.577Å
α: 89.97° β: 90.18° γ: 89.98°
R-values:
R R work R free
0.189 0.187 0.238
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Medical Countermeasures against Ricin Intoxication.
Rasetti-Escargueil et al. (2023)
2 other articles