7kej

Electron Microscopy
3.8Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-211930 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (5 distinct):
GP1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 313 amino acids
Theoretical weight: 34.98 KDa
Source organism: Ebola virus - Mayinga, Zaire, 1976
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05320 (Residues: 32-309; Coverage: 43%)
Gene name: GP
Sequence domains: Filovirus glycoprotein
Antibody Fab heavy chain (HC) BDBV-289 Chains: G, H, I
Molecule details ›
Chains: G, H, I
Length: 251 amino acids
Theoretical weight: 26.86 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Antibody Fab light chain (LC) BDBV-289 Chains: J, K, L
Molecule details ›
Chains: J, K, L
Length: 231 amino acids
Theoretical weight: 24.73 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
GP2 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 203 amino acids
Theoretical weight: 22.16 KDa
Source organism: Zaire ebolavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05320 (Residues: 461-633; Coverage: 27%)
Gene name: GP
Sequence domains: Envelope glycoprotein GP2-like, HR1-HR2

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-22839
Expression system: Homo sapiens