› 7kv3

X-ray diffraction
2.05Å resolution

Surface glycan-binding protein A from Bacteroides thetaiotaomicron in complex with laminarihexaose

Released:
DOI: 10.2210/pdb7kv3/pdb
PDB entry 7kv3 coloured by chain, front view.
PDB entry 7kv3 coloured by chain, side view.
PDB entry 7kv3 coloured by chain, top view.
Source organism: Bacteroides thetaiotaomicron
Primary publication:
Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota.
Tamura K, Dejean G, Van Petegem F, Brumer H
J Biol Chem 296 100415
PMID: 33587952

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-103117 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
RagB/SusD family nutrient uptake outer membrane protein Chain: AAA
Molecule details ›
Chain: AAA
Length: 515 amino acids
Theoretical weight: 59.35 KDa
Source organism: Bacteroides thetaiotaomicron
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A173VPY3 (Residues: 1-515; Coverage: 100%)
Gene names: DW011_12550, DW780_14665, DWY18_18425, FIB20_21255, GAN59_19940
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC
Carbohydrate polymer
1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Unit cell:
a: 76.024Å b: 72.937Å c: 101.484Å
α: 90° β: 105.644° γ: 90°
R-values:
R R work R free
0.159 0.157 0.204
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Cell Surface Xyloglucan Recognition and Hydrolysis by the Human Gut Commensal Bacteroides uniformis.
Grondin et al. (2022)
8 other articles

2 mentions without citation

Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota.
Tamura et al. (2021)
1 more