› 7lru

X-ray diffraction
1.6Å resolution

Crystal structure of SFPQ-NONO-SFPQ chimeric protein homodimer

Released:
DOI: 10.2210/pdb7lru/pdb
PDB entry 7lru coloured by chain, front view.
PDB entry 7lru coloured by chain, side view.
PDB entry 7lru coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Marshall AC, Bond CS, Mohnen I, Knott GJ

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149900 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-POU domain-containing octamer-binding protein; Splicing factor, proline- and glutamine-rich Chain: B
Molecule details ›
Chain: B
Length: 263 amino acids
Theoretical weight: 30.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P23246 (Residues: 276-456, 505-535; Coverage: 30%)
  • Canonical: Q15233 (Residues: 234-281; Coverage: 10%)
Gene names: NONO, NRB54, PSF, SFPQ
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: C2221
Unit cell:
a: 73.665Å b: 107.162Å c: 68.305Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.218 0.256
Expression system: Escherichia coli BL21(DE3)

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