7nx8

X-ray diffraction
1.95Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-534872 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
EY6A Fab heavy chain Chain: H
Molecule details ›
Chain: H
Length: 226 amino acids
Theoretical weight: 24.35 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
EY6A Fab light chain Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S1 Chain: E
Molecule details ›
Chain: E
Length: 205 amino acids
Theoretical weight: 23.12 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 333-528; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
COVOX-222 Fab heavy chain Chain: A
Molecule details ›
Chain: A
Length: 224 amino acids
Theoretical weight: 23.46 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
COVOX-222 Fab light chain Chain: B
Molecule details ›
Chain: B
Length: 214 amino acids
Theoretical weight: 23.33 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 54.843Å b: 122.727Å c: 213.859Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.223 0.246
Expression system: Homo sapiens