7q8v

X-ray diffraction
2.13Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178328 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tau-tubulin kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 309 amino acids
Theoretical weight: 35.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5TCY1 (Residues: 13-320; Coverage: 23%)
Gene names: BDTK, KIAA1855, TTBK1
Sequence domains: Protein kinase domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 170.915Å b: 39.519Å c: 49.037Å
α: 90° β: 103.08° γ: 90°
R-values:
R R work R free
0.19 0.187 0.244
Expression system: Escherichia coli BL21(DE3)