Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Neurotransmitter-gated ion-channel
- Gamma-aminobutyric acid A receptor/Glycine receptor alpha
- Gamma-aminobutyric-acid A receptor, beta subunit
- Neurotransmitter-gated ion-channel ligand-binding domain superfamily
- Gamma-aminobutyric-acid A receptor, alpha subunit
- Neurotransmitter-gated ion-channel transmembrane domain
- Neurotransmitter-gated ion-channel transmembrane domain superfamily
- Neuronal acetylcholine receptor
10 more domains
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-276163 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (6 distinct):
Gamma-aminobutyric acid receptor subunit alpha-4
Molecule details ›
Chain: A
Length: 554 amino acids
Theoretical weight: 61.7 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 554 amino acids
Theoretical weight: 61.7 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P48169 (Residues: 1-554; Coverage: 100%)
Sequence domains:
Gamma-aminobutyric acid receptor subunit beta-3
Molecule details ›
Chains: B, D, E
Length: 473 amino acids
Theoretical weight: 54.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 473 amino acids
Theoretical weight: 54.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P28472 (Residues: 1-473; Coverage: 100%)
Sequence domains:
Gamma-aminobutyric acid receptor subunit gamma-2
